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. Author manuscript; available in PMC: 2018 Apr 12.
Published in final edited form as: Sci Transl Med. 2017 Apr 12;9(385):eaai9321. doi: 10.1126/scitranslmed.aai9321

Fig. 6. Gene expression correlating with clinical parameters of coagulopathy during EVD.

Fig. 6

(A) Serum D-dimer (μg/ml, left axis) and platelet levels (K/μl, right axis) and heatmap showing expression profiles of transcripts (n = 1016) with expression levels that are correlated positively with serum D-dimer levels (≥.6) and negatively with platelet levels (≤-0.6). (B) Gene ontology analysis of transcripts, with expression levels correlating with serum D-dimer and platelet values (activation Z score is based on d10 expression values). (C) Expression profiles of transcripts involved in macrophage recruitment, neutrophil recruitment, antiviral response, macrophage cell death, degranulation, and phagocytosis.