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. 2015 Nov 16;1(3):97–104. doi: 10.5114/ceh.2015.55566

Table 1.

Dosage regimens of drugs included in the recommendations (drugs in different groups are listed alphabetically)

Drug category Class Drugs Daily dosage
Direct acting antivirals (DAA) NS3 inhibitors (proteases) Asunaprevir (ASV)
Boceprevir (BOC)
Paritaprevir (PTV)
Simeprevir (SMV)
Telaprevir (TVR)
200 mg/day in 2 doses
2,400 mg/day in 3 doses
150 mg/day in 1 dose*
150 mg/day in 1 dose
2,250 mg/day in 2 doses
NS5B inhibitors (polymerases) Dasabuvir (DSV)
Sofosbuvir (SOF)
500 mg/day in 2 doses
400 mg/day in 1 dose**
NS5A inhibitors Daclatasvir (DCV)
Ledipasvir (LDV)
Ombitasvir (OBV)
60 mg/day in 1 dose
90 mg/day in 1 dose**
25 mg/day in 1 dose*
Interferons Pegylated interferons α (PegIFNα) PegIFNα2α
PegIFNα2β
180 μg/week
1.5 μg/kg/week
Others Ribavirin (RBV) 1,000 or 1,200 mg at body weight < 75 kg or > 75 kg
*

PTV and OBV are combined in one tablet with ritonavir (PTV/OBV/r)

**

SOF can be combined in one tablet with LDV (SOF/LDV)