Table 5.
Genotype | Population | Drugs | Duration of therapy |
---|---|---|---|
1, 2, 3, 4, 5, 6 | Approved for liver transplantation | SOF + RBV | Until transplantation, not longer than 24 weeks |
1, 4 | PTV/OBV/r + DSV + RBV (G1) PTV/OBV/r + RBV (G4) SOF/LDV + RBV |
12 weeks in G1b infection (if Child-Pugh A; 24 weeks in G1a or G4 infection) 24 weeks |
|
1, 3, 4, 5, 6 | Post liver transplantation | SOF + DCV +/– RBV | 12-24 weeks |
2 | SOF + RBV | 12-24 weeks | |
1, 4 | PTV/OBV/r + DSV + RBV (G1) PTV/OBV/r + RBV (G4) SOF/LDV + RBV SOF + SMV +/– RBV |
24 weeks 24 weeks 24 weeks 12-24 weeks |