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. 2015 Nov 16;1(3):97–104. doi: 10.5114/ceh.2015.55566

Table 5.

Therapeutic options for patients prior to and after liver transplantation

Genotype Population Drugs Duration of therapy
1, 2, 3, 4, 5, 6 Approved for liver transplantation SOF + RBV Until transplantation, not longer than 24 weeks
1, 4 PTV/OBV/r + DSV + RBV (G1)
PTV/OBV/r + RBV (G4)
SOF/LDV + RBV
12 weeks in G1b infection (if Child-Pugh A; 24 weeks in G1a or G4 infection)
24 weeks
1, 3, 4, 5, 6 Post liver transplantation SOF + DCV +/– RBV 12-24 weeks
2 SOF + RBV 12-24 weeks
1, 4 PTV/OBV/r + DSV + RBV (G1) PTV/OBV/r + RBV
(G4)
SOF/LDV + RBV
SOF + SMV +/– RBV
24 weeks

24 weeks
24 weeks
12-24 weeks