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| HBV variants | Sensitivity level | ||||
|---|---|---|---|---|---|
| LMV | LdT | ETV | ADV | TDF | |
| Wild type | S | S | S | S | S |
| M204V | R | S | I | I | S |
| M204I | R | R | I | I | S |
| L180M + M204V | R | R | I | I | S |
| A181T/V | I | S | S | R | S |
| N236T | S | S | S | R | I |
| L180M + M204V/I ± I169T ± V173L ± M250V | R | R | R | S | S |
| L180M + M204V/I ± T184G ± S202I/G | R | R | R | S | S |
LMV – lamivudine, LdT – telbivudine, ETV – entecavir, ADV – adefovir, TDF – tenofovir disoproxil, S – sensitive, I – reduced sensitivity, R – resistant
