Table 1.
Antibacterial activity of the three compounds (100 μmol/L) against six strains in vitro.
| Compounds | Inhibition rate (%) | |||||
|---|---|---|---|---|---|---|
| E. coli ATCC 25922 | B. subtilis ATCC 6051 | S. aureus ATCC 25923 | A. baumannii ATCC BAA-1710D | K. pneumonia ATCC BAA-1705 | P. aeruginosa ATCC 39324 | |
| 1a | 11.33 ± 7.24 | Inactive | 91.51 ± 7.98∗∗ | 8.51 ± 1.35 | 5.03 ± 2.36 | Inactive |
| 1b | 16.55 ± 4.22 | Inactive | Inactive | 10.05 ± 2.46 | 8.07 ± 1.23 | 1.38 ± 1.26 |
| 1c | 0.55 ± 2.19 | Inactive | Inactive | 14.40 ± 3.59 | 13.54 ± 4.58 | 8.65 ± 3.58 |
| Ampicillin | 99.34 ± 3.26 | — | — | — | — | — |
| Streptomycin | — | 94.12 ± 6.56 | 97.05 ± 4.24 | — | — | — |
| Kanamycin | — | — | 87.34 ± 3.19 | — | ||
| Chloramphenicol | — | — | — | 82.43 ± 9.29 | — | 86.65 ± 7.37 |
Values are mean ± standard deviation of three independent experiments. The bacteria were seeded in 96-well microplates at concentration of 1 × 105 CFU/mL in Luria Broth medium. Tested compounds and positive controls were added to a final concentration of 100 μmol/L. Inhibiting growth of the bacteria was determined at 450 nm using an ELISA plate reader after shaking on a vibrating platform at 37°C for 8 h. ∗∗P < 0.01 compared with the control.