Table 2.
Age-adjusted univariate Cox analyses for total mortality—individuals with or without diabetes. A 12 1/2-year follow-up of the Oslo II study of 2000.
| Risk factors | Total mortality | |||||
|---|---|---|---|---|---|---|
| Diabetes n = 425 n fatal cases = 241 |
Nondiabetes n = 6009 n fatal cases = 2078 |
|||||
| HR | 95% CI | p value | HR | 95% CI | p value | |
| Oral health | ||||||
| Total number of extractions, n | 1.01 | 0.99–1.02 | 0.245 | 1.01 | 1.01–1.02 | <0.001 |
| Total number of tooth extractions by group, test of trend | 1.03 | 0.93–1.14 | 0.556 | 1.04 | 1.002–1.08 | 0.042 |
| Total number of tooth extractions by group | ||||||
| 1 = 0-1, reference | 1.00 | — | — | 1.00 | — | — |
| 2 = 2–4 | 1.01 | 0.73–1.39 | 0.960 | 0.84 | 0.75–0.93 | 0.010 |
| 3 = 5–8 | 0.86 | 0.57–1.30 | 0.478 | 0.86 | 0.75–0.99 | 0.033 |
| 4 = 9–31 | 1.14 | 0.79–1.66 | 0.477 | 1.15 | 1.001–1.32 | 0.049 |
| 5 = 32 | 1.23 | 0.67–2.24 | 0.502 | 1.49 | 1.19–1.87 | 0.001 |
| Tooth extraction by infection (TE) | 0.93 | 0.72–1.21 | 0.58 | 1.09 | 0.996–1.187 | 0.06 |
| Periodontitis (PI) | 1.13 | 0.74–1.71 | 0.58 | 0.997 | 0.824–1.207 | 0.98 |
| TE and PI combined (OI) | 0.92 | 0.71–1.20 | 0.53 | 1.11 | 1.02–1.21 ∗ | 0.02 |
| General measurements | ||||||
| Age in 2000 years | 1.13 | 1.09–1.17 | <0.01 | 1.13 | 1.12–1.14 | <0.01 |
| Glucose nonfasting mmol/l | 0.995 | 0.96–1.03 | 0.73 | 1.07 | 1.04–1.10 | <0.01 |
| Systolic blood pressure mmHg | 1.003 | 0.997–1.01 | 0.30 | 1.004 | 1.002–1.006 | <0.01 |
| BMI Kg/mm2 | 0.998 | 0.96–1.03 | 0.91 | 0.995 | 0.98–1.01 | 0.44 |
| Total cholesterol mmol/l | 1.07 | 0.95–1.21 | 0.26 | 0.93 | 0.89–0.97 | <0.01 |
| Triglycerides mmol/l | 1.07 | 0.97–1.17 | 0.18 | 0.996 | 0.95–1.04 | 0.858 |
| HDL mmol/l | 1.16 | 0.84–1.59 | 0.38 | 0.95 | 0.88–1.06 | 0.337 |
| hs-CRP mmol/l n diabetes 331 n nondiabetes 4662 |
1.02 | 1.01–1.03 | 0.01 | 1.01 | 1.004–1.01 | <0.01 |
| hs-CRP mmol/l quartile values | ||||||
| 1 = 0–0.81, reference | 1.00 | — | — | 1.00 | — | — |
| 2 = 0.82–1.67 | 0.66 | 0.42–1.05 | 0.078 | 1.09 | 0.94–1.27 | 0.243 |
| 3 = 1.68–3.46 | 0.72 | 0.45–1.16 | 0.181 | 1.27 | 1.10–1.47 | 0.001 |
| 4 = 3.47+ | 1.43 | 0.94–2.18 | 0.098 | 1.84 | 1.60–2.11 | <0.001 |
| Alcohol drinking 4–7 times per week |
0.82 | 0.62–1.09 | 0.17 | 1.10 | 1.002–1.20 | 0.045 |
| Daily smoking Yes |
1.25 | 0.91–1.72 | 0.17 | 1.92 | 1.74–2.11 | <0.01 |
| Level of education 1–12 |
0.997 | 0.96–1.03 | 0.85 | 0.96 | 0.95–0.97 | <0.01 |
∗Bold indicates p value <0.05.