Table 1.
Baseline characteristics of patients with hepatocellular carcinoma complicated with bile duct invasion at the time of initial diagnosis (N=247)
| Variable | Value |
|---|---|
| Age (years) | 56 (49-64) |
| Sex, male | 206 (83.4) |
| Etiology, HBV/HCV/alcohol/others | 176/18/14/39 (71.2/7.3/5.7/15.8) |
| Child-Pugh class, A/B/C | 115/111/21 (46.6/44.9/8.5) |
| Serum total bilirubin | 1.6 (1.0-5.3) |
| <3.0 / ≥3.0 mg/dL | 159/88 (64.4/35.6) |
| Serum alpha-fetoprotein (ng/mL) | 957.5 (49.4-25825.0) |
| Tumor number, single/multiple | 94/153 (38.1/61.9) |
| Tumor size (cm) | 8.0 (5.2-11.0) |
| PVTT, none/unilateral/main or bilateral | 81/86/80 (32.8/32.4/34.8) |
| Level of bile duct involvement | |
| Segmental bile duct | 74 (30.0) |
| Unilateral 1st brach duct | 82 (33.2) |
| Bilateral or common bile duct | 91 (36.8) |
| Extra-hepatic metastasis | 53 (21.4) |
| Lung / lymph node / bone / adrenal gland | 25/20/5/3 (10.1/8.1/2.0/1.2) |
| BCLC stage, A/B/C/D | 33/29/165/20 (13.4/11.7/66.8/8.1) |
All values are expressed as median (interquartile range) or number (%).
HBV, hepatitis B virus; HCV, hepatitis C virus; PVTT, portal vein tumor thrombus; BCLC, Barcelona Clinic Liver Cancer.