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. Author manuscript; available in PMC: 2018 Jan 11.
Published in final edited form as: J Am Chem Soc. 2016 Dec 23;139(1):417–425. doi: 10.1021/jacs.6b11097

Table 2.

Screening of Ligands for meta-C-H Arylation of Phenethylamine-Derived Sulfonamidea,b

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a

Reaction conditions: substrate 1a (0.1 mmol), methyl 2-iodobenzoate 2a (3.0 equiv), Pd(OAc)2 (10 mol%), ligand (20 mol%), 2-norbornene (1.5 equiv), AgOAc (3.0 equiv), TBME (1.0 mL), 95 °C, air, 24 h.

b

Yield of product 3aa was determined by 1H NMR using dibromomethane as an internal standard.