. Author manuscript; available in PMC: 2017 Jul 5.

Published in final edited form as: Arthritis Care Res (Hoboken). 2011 Dec;63(12):1680–1690. doi: 10.1002/acr.20629

Table 2.

Summary of Drug Course Information - Mean (S.D.)

Course	Full Cohort			Incident User Cohort			Established User Cohort
Course	MPR<80% (n=71)	MPR ≥80% (n=384)	p-value	MPR<80% (n=17)	MPR ≥80% (n=68)	p-value	MPR<80% (n=54)	MPR ≥80% (n=316)	p-value
Average prescribed weekly dose, (mg/wk)^†	16 (4)	16 (4)	0.6	15 (3)	16(4)	0.44	16 (4)	16 (4)	0.95
Average observed weekly dose, (mg/wk)^‡	11 (3)	16 (5)	<0.001	10 (2)	16 (6)	<0.001	12 (3)	16 (5)	<0.001
Total Prescribed duration, days^¥	654 (599)	1345 (975)	<0.001	350 (320)	605 (382)	0.02	749 (634)	1504 (1395)	<0.01
Observed Course Duration, days^¶	902 (783)	1370 (980)	<0.001	497 (410)	592 (374)	0.36	1029 (803)	1536 (14727)	<0.01
Course total dose, (mg)^§	1492 (1425)	3154 (2490)	<0.001	768 (770)	1421 (1079)	0.02	1720 (1307)	3527 (3245)	<0.01

= P <0.05 and marked in bold

^†

Average prescribed dose is the course total dose (mg) during the course divided by the total prescribed duration (weeks).

^‡

Average observed dose is the course total dose (mg) during the course divided by the total course duration.

^¥

Total prescribed duration was the sum of all the expected prescription durations for each prescription over the course.

^¶

The observed course duration was the time from the date of the first prescription to the end of the final prescription in a course.

^§

The course total dose was the total number of mgs dispensed with each prescription over the course.