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. 2017 Jun 25;108(7):1405–1413. doi: 10.1111/cas.13276

Figure 7.

Figure 7

p62‐RIP1‐NF‐κB regulation pathway in ovarian cancer cells. p62 activating the NF‐κB pro‐survival pathway depends on K63‐ubiquitinated RIP1 with cisplatin treatment. Furthermore, the activation of nuclear factor‐ κB (NF‑κB) promotes the transcription of target pro‐survival genes.