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. 2017 May 22;108(7):1440–1446. doi: 10.1111/cas.13265

Table 3.

Patients with suspected pathogenic germline variants

Patient Age Sex Tumor type Family history Gene Mutation Germline testing†
1 44 M Pancreatic BRCA2 p.Gln3026*
2 78 F Colorectal TP53 p.Arg273His
3 57 M Colorectal TP53 p.Gly245Asp Somatic
4 39 F Breast (HBOC) + BRCA1 p.Leu63* Germline
5 82 M Gastric BRCA1 p.Gln934* Germline
TP53 p.Arg175His Somatic

HBOC, hereditary breast and ovarian cancer. †Patients 1 and 2 did not desire to undergo germline testing.