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. 2017 Jul 5;12(7):e0180539. doi: 10.1371/journal.pone.0180539

Table 3. Top ranked candidates with multiple B terms of metabolites.

Rank A term Relation
(→)
1st B term Relation
(→)
2nd B term Relation
(→)
3rd B term Relation
(→)
C term Average Semantic Relatedness
1 LacCer
(MB)
Contain Inulobiose
(MB)
Co-occur 4-Aminohippuric acid
(MB)
Co-occur - - Arterial Stiffness
(BP)
0.1438
2 LacCer
(MB)
Co-occur Nitric Oxide
(MB)
Co-occur Malondialdehyde
(MB)
Increase - - Arterial Stiffness
(BP)
0.0270
3 LacCer
(MB)
Increase Phosphate
(MB)
Co-occur Folic acid
(MB)
Decrease - - Arterial Stiffness
(BP)
0.0197
4 LacCer
(MB)
Increase Phosphate
(MB)
Co-occur Hydrogen carbonate
(MB)
Contain Sucrose
(MB)
Co-occur Arterial Stiffness
(BP)
0.0036
5 LacCer
(MB)
Plain Silicon
(MB)
Plain Hydrogen carbonate
(MB)
Contain Sucrose
(MB)
Co-occur Arterial Stiffness
(BP)
-0.0021
6 LacCer
(MB)
Increase LacCer surfate
(MB)
Plain Phospholipid
(MB)
Report - - Arterial Stiffness
(BP)
-0.0034

In the Entity columns, square brackets contain the biological type information of the corresponding entity. (MB): Metabolite, (GE): Gene/Protein, (BP): Biological Process/Pathway, (DS): Disease, and (BD): Body/Organ. LacCer is the acronym for lactosylceramide. ‘Plain’ describes relations that did not have causality nor can be classified by our category, due to the ‘verb’ extracted between two entities have no causality nor can it be classified by our category. While, ‘co-occurrence’ a ‘verb’ does not exist to describe the relation.