Table 3.
Estimates of Heritability and Shared Environment for Specific Types of Cancer in the NorTwinCan Cohorta
| Familial Risk, % (95% CI) | ||
|---|---|---|
| Heritability | Shared Environment | |
| Overall cancer | 33 (30-37) | 0 |
| Head and neck | 9 (0-60) | 26 (0-65) |
| Stomach | 22 (0-55) | 6 (0-31) |
| Colon | 15 (0-45) | 16 (0-38) |
| Rectum and anus | 14 (0-50) | 10 (0-38) |
| Lung | 18 (0-42) | 24 (7-40) |
| Skin | ||
| Melanoma | 58 (43-73) | 0 |
| Nonmelanoma | 43 (26-59) | 0 |
| Breast | 31 (11-51) | 16 (0-31) |
| Corpus uteri | 27 (11-43) | 0 |
| Ovary | 39 (23-55) | 0 |
| Prostate | 57 (51-63) | 0 |
| Testis | 37 (0-93) | 24 (0-70) |
| Kidney | 38 (21-55) | 0 |
| Bladder, other urinary organs | 30 (0-67) | 0 |
| Leukemia, other | 57 (0-100) | 0 |
Abbreviation: NorTwinCan, Nordic Twin Study of Cancer.
Not calculated for cancer types with less than 5 concordant pairs.