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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Exp Parasitol. 2017 Jan 5;180:71–83. doi: 10.1016/j.exppara.2017.01.001

Fig. 4. BKI-1294 induces the formation of multinucleated parasite complexes in N.caninum infected cells.

Fig. 4

A: TEM showing a parasitophorous vacuole containing numerous N. caninum tachyzoites cultured in the absence of BKI-1294. B. N. caninum tachyzoites were allowed to invade the host cells and were then treated with BKI-1294 (2.5μM) for 6 days. Note the formation of multinucleated parasites, still enclosed within a vacuole. n = parasite nucleus; hn = host cell nucleus. Bars = 1 μm