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. 2017 Jul 6;8:442. doi: 10.3389/fphar.2017.00442

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Copyright © 2017 Shenoy, Kuo, Vetter and Smith.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Radiological assessment of tibiae from BCIBP rats and corresponding sham rats. Panels in the figure show (A) 3D-μCT radiological image of a sham rat’s tibia at day 10 post-ITI, (B) trabecular bone of a sham rat’s tibia at day 10 post-ITI, (C) 3D-μCT radiological image of a BCIBP rat’s tibia at day 10 post-ITI, (D) trabecular bone of a BCIBP rat’s tibia at day 10 post-ITI, (E–H) morphometric changes in BCIBP rats’ tibiae relative to sham rats’ tibiae at day 10 post-ITI, (I) 3D-μCT radiological image of a sham rat’s tibia at day 48 post-ITI, (J) trabecular bone of a sham rat’s tibia at day 48 post-ITI, (K) 3D-μCT radiological image of a BCIBP rat’s tibia at day 48 post-ITI, (L) trabecular bone of a BCIBP rat’s tibia at day 48 post-ITI, (M–P) morphometric changes in BCIBP rats’ tibiae relative to sham rats’ tibiae at day 48 post-ITI. ^∗p ≤ 0.05 (Two-way ANOVA, post hoc Bonferroni test). Scale bar – 5 mm.