Figure 7.

Effects of TUDCA on the TUNEL-positive neuronal cells at 72 h after TBI. Representative microphotographs showing the colocalization of TUNEL (green)-positive cells with neuronal cells (red) in the lesion area of the cerebral cortex and the dentate gyrus of the ipsilateral hippocampus at 72 h after TBI (A). Quantitative data indicating that TUNEL-positive neuronal cells was greater in TBI group than in TUDCA treated group both in the lesion area (B) and in the dentate gyrus (C). All the results are expressed as the mean ± SEM, and n = 5 for each group. *p < 0.05 vs. sham; ^#p < 0.05 vs. control. Scale bar = 50 μm.