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. 2017 Jul 5;7:4712. doi: 10.1038/s41598-017-04967-0

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Tyrosine kinase activity in primary tumour, xenograft tumours, and the cell lines. (a) Tyrosine kinase activity detected with an array of peptide substrate is fully shown in the left panel and the signal intensities of the top 20 peptides are shown in the right panel. 1: tumour tissue, 2: NCC-CDS1-X1 tumour tissue, 3: NCC-CDS1-X3 tumour tissue, 4: NCC-CDS1-X1-C1 cells, 5: NCC-CDS1-X3-C1 cells. (b) Western blotting analysis of Src. Arrowheads indicate the position of Src with a molecular weight of 60 kDa. Full-length blots are shown in Supplementary Fig. S3.