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. 2017 Jul 5;7:4628. doi: 10.1038/s41598-017-04915-y

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Serotype specific propensity of whether a given serotype/serogroup is more likely to be found as a primary or non-primary isolate. Pneumococcal serotypes identified from nasopharyngeal swabs of black South-African children were classified according to whether they occurred as a primary or non-primary isolate as determined by carriage density. Single colonizers were included in the analysis as primary isolates. The box at the top of the graph is an inset of the blocked region at the bottom. *Results were considered significant when the p-value was < 0.05.