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Yield of culture and molecular qPCR for the detection Streptococcus pneumoniae in nasopharyngeal swabs (n = 374).
| qPCR (−) | qPCR (+) | Total | p-value | Concordance (kappa) | PPV | NPV | Sensitivity (%) | Specificity (%) | |
|---|---|---|---|---|---|---|---|---|---|
| Culture (+) | 8(2) | 258(69) | 266(71) | <0.001 | 0.58 | 0.97 | 0.55 | 84 | 88 |
| Culture (−) | 59(16) | 49(13) | 108(29) | ||||||
| Total | 67(18) | 307(82) | 374(100) |
Numbers are value (%), p-values of <0.05 were considered significant. PPV, positive predictive value. NPV, negative predictive value.
