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. 2017 Jul 6;8:1201. doi: 10.3389/fmicb.2017.01201

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Copyright © 2017 Kavitha and Savithri.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of culture media on the yields of antimicrobial metabolites of actinobacterial strains (A) A1 and A2, (B) A3 and A4, (C) A5 and A6, and (D) A7 and A8. Arginine-glycerol (Arg-Gly), Czapek-Dox (Dox), ISP-1, ISP-2, ISP-4, Luria broth (LB), Maltose-tryptone (MT), nutrient broth (NB), Starch-casein (SC), Yeast mannitol broth (YMB), and Yeast extract-peptic digest of animal tissue-dextrose (YPD) broths. ISP-2 medium supported better yields of antimicrobial metabolites for majority of the strains (A1, A3, A4, A5, and A6) whereas the strain A2 preferred starch casein broth for its antimicrobial activity. Other strains, A7 and A8 elaborated high antimicrobial activity when grown in ISP-1 medium. Data was statistically analyzed by Two-way ANOVA and found to be significant at 5% level (P < 0.05) between the strains.