Table 2.
Hazard ratios of different variables on ischemic lower-extremity PAD in hemodialysis patients.
| Variable | Model 1 | Model 2 | ||
|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | |
| L5% | 1.75 (1.43–2.13) | <0.001 | 1.54 (1.14–2.10) | 0.005 |
| IHD | 0.18 (0.07–0.48) | 0.001 | 4.85 (1.59–14.76) | 0.005 |
| Cholesterol | 1.02 (1.01–1.03) | <0.001 | 1.01 (0.99–1.03) | 0.28 |
| LDL-C | 1.02 (1.01–1.04) | 0.002 | 1.01 (0.99–1.04) | 0.19 |
| Hs-CRP | 2.16 (1.34–3.47) | <0.001 | 0.90 (0.46–1.78) | 0.51 |
| DM | 0.17 (0.07–0.44) | <0.001 | 1.36 (0.38–4.85) | 0.63 |
| Age | 1.06 (1.01–1.11) | 0.008 | 1.03 (0.98–1.10) | 0.19 |
| HD Vintage | 0.98 (0.96–1.01) | 0.079 | — | — |
| Sex | 0.40 (0.14–1.10) | 0.076 | — | — |
| Hypertension | 0.19 (0.02–1.47) | 0.11 | — | — |
| Smoking | 2.93 (0.39–21.85) | 0.29 | — | — |
| Calcium | 1.11 (0.57–2.13) | 0.76 | — | — |
| Phosphate | 1.20 (0.73–1.96) | 0.46 | — | — |
| BMI | 1.15 (0.98–1.34) | 0.075 | — | — |
Model 1 = crude hazard ratio; Model 2 = adjusted for L5%, IHD, LDL-C, Hs-CRP, DM, and age. BMI = body mass index; DM = diabetes mellitus; HD = hemodialysis; HR = hazard ratio; Hs-CRP = high-sensitivity C-reactive protein; IHD = ischemic heart disease; LDL-C = low-density lipoprotein-cholesterol; PAD = peripheral artery disease.