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. 2017 Jul 5;7:4644. doi: 10.1038/s41598-017-04484-0

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Imaging time course of ASCs and macrophotographs showing the process of wound-healing on an example of transplantation of AA-preconditioned, syngeneic, SPIO- or ¹⁹F-labeled ASCs to young animals. The ¹⁹F images, BLI, and MACRO pictures belong to the same animal, while T2* images were derived from another animal. Arrows indicate the hypothetical location of iron oxide-labeled cells on T2* MRI, but data are inconclusive. ¹⁹F MRI shows clear hot spot images of cell deposits. T2w MRI presents an anatomical reference for ¹⁹F MRI. The BLI signal is represented as a color-coded map. The macro pictures depict the time course of wound-healing.