Monosaccharide nomenclature |
Glc |
Glucose |
GlcNAc |
2-N-acetylglucosamine |
Gal |
Galactose |
GalNAc |
2-N-acetylgalactosamine |
Man |
Mannose |
Fuc |
Fucose |
NeuAc |
5-N-acetylneuraminic acid |
Sialic acid |
A general term for neuraminic acids |
Hex |
Hexose (e.g., Glc or Gal or Man) |
HexNAc |
N-acetylhexosamine (e.g., GlcNAc or GalNAc) |
dHex |
Deoxyhexose (e.g., Fuc) |
Other terminologies |
Reducing end |
The reducing end of a glycan is the monosaccharide with a free anomeric carbon that is not involved in a glycosidic bond and is thus capable of converting to the open ring form |
Permethylation |
Derivatization of all OH to O-methyl and NH to N-methyl |
Glycosidic bond |
Covalent bonds associated with carbohydrates |
Cross-ring cleavage |
Fragmentation across a monosaccharide ring |
Scar |
A nonmethylated hydroxyl group of glycan exposed by tandem MS fragmentation of a glycosidic bond in a permethylated glycan |
β-Elimination |
Release of O-glycosidic linkages between glycans and the β-hydroxyl groups of serine or threonine |