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. 2017 Jul 5;7:4716. doi: 10.1038/s41598-017-05096-4

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Nopal consumption modifies the intestinal microbiota. (A) Alpha diversity and rarefaction curves. (B) Principal components analysis of the (C), HFS, HFS + N, HFS-C + N and HFS-C groups, n = 5 per group, (C) Relative abundance of Firmicutes and Bacteriodetes, (D) relative abundance of gut microbiota at the genus level, (E) and at species level and (F) heatmap of the ten bacterial species with greatest differences among groups.