Table 3.
Relationship of outcome to various characteristics
Variable | Outcome | p -value* | ||||
---|---|---|---|---|---|---|
Non-survivors (n=131) | Survivors (n=162) | |||||
Age (months) | Mean ± SD | 28.0±35.2 | 26.5±33.8 | 0.3 | ||
Median | 8.0 | 9.0 | ||||
Age groups n (%) | < 1 year | 71 | 54.2 | 82 | 50.6 | 0.6 |
1 – 6 years | 44 | 33.6 | 63 | 38.9 | 0.4 | |
> 6 years | 16 | 12.2 | 17 | 10.5 | 0.7 | |
Sex n (%) | Male | 69 | 52.7 | 93 | 57.4 | 0.5 |
Female | 62 | 47.3 | 69 | 42.6 | ||
PRISM III on admission | Mean ± SD | 23.7±11.6 | 8.2±3.9 | <0.001 | ||
Median | 20.0 | 8.0 | ||||
Cause n (%) | Medical | 118 | 90.1 | 151 | 93.2 | 0.4 |
Surgical | 13 | 9.9 | 11 | 6.8 | ||
Reason for admission n, % | Neurological | 40 | 30.5 | 61 | 37.7 | 0.2 |
Respiratory | 19 | 14.5 | 46 | 28.4 | 0.005 | |
Cardiac | 33 | 25.2 | 21 | 13.0 | 0.010 | |
Sepsis | 24 | 18.3 | 10 | 6.2 | 0.002 | |
Neuromuscular disease | 4 | 3.1 | 12 | 7.4 | 0.1 | |
Renal | 4 | 3.1 | 2 | 1.2 | 0.4 | |
Post-operative | 0 | 0.0 | 2 | 1.2 | 0.5 | |
Others | 7 | 5.3 | 8 | 4.9 | 1.0 | |
Reason for initiation of ventilation n, % | Neurologic | 47 | 35.9 | 67 | 41.4 | 0.4 |
Respiratory failure | 19 | 14.5 | 52 | 32.1 | 0.001 | |
Cardiovascular failure | 37 | 28.2 | 21 | 13.0 | 0.002 | |
Sepsis | 24 | 18.3 | 10 | 6.2 | 0.002 | |
Neuromuscular | 4 | 3.1 | 12 | 7.4 | 0.1 | |
FIO2/PaO2 n (%) | < 200 | 59 | 45.0 | 51 | 31.5 | 0.02 |
200–300 | 38 | 29.0 | 78 | 48.1 | 0.001 | |
> 300 | 34 | 26.0 | 33 | 20.4 | 0.3 | |
ARDS n, % | Yes | 19 | 14.5 | 7 | 4.3 | 0.003 |
No | 112 | 85.5 | 155 | 95.7 | ||
Airways n, % | Endotracheal tube | 131 | 100.0 | 158 | 97.5 | 0.1 |
Tracheostomy | 0 | 0.0 | 4 | 2.5 | ||
Mechanical ventilation duration n, % | Mean ± SD | 8.5±6.9 | 17.5±19.5 | <0.001 | ||
Median | 7.0 | 10.0 | ||||
Complications n, % | Yes | 64 | 48.9 | 53 | 32.7 | 0.006 |
No | 67 | 51.1 | 109 | 67.3 | ||
VAP† (%) | Yes | 47 | 35.9 | 33 | 20.4 | 0.004 |
No | 84 | 64.1 | 129 | 79.6 | ||
Pneumothorax n, % | Yes | 19 | 14.5 | 12 | 7.4 | 0.06 |
No | 112 | 85.5 | 150 | 92.6 | ||
Atelectasis n, % | Yes | 3 | 2.3 | 10 | 6.2 | 0.2 |
No | 128 | 97.7 | 152 | 93.8 | ||
PES‡ n, % | Yes | 3 | 2.3 | 4 | 2.5 | 1.0 |
No | 128 | 97.7 | 158 | 97.5 | ||
MODS§ n, % | Yes | 98 | 74.8 | 23 | 14.2 | <0.001 |
No | 33 | 25.2 | 139 | 85.8 |
p value less than 0.05 is significant,
VAP: ventilator-associated pneumonia,
PES: post extubation stridor,
MODS: multiple organ dysfunction syndrome