Table 2.
Resistance genes, plasmids and phages identified in K. pneumoniae EA-MEH.
| Predicted phenotype | Resistance gene | Position in contig |
|---|---|---|
| Aminoglycoside resistance | aph(3′)-Ia | 143..956 |
| aac(6′)Ib-cr | 1878..2477 | |
| armA | 3442..4215 | |
| strB | 3710..4546 | |
| strA | 4546..5349 | |
| aadA2 | 634..1425 | |
| Beta-lactam resistance | blaSHV-28 | 12372..13232 |
| blaCTX-M-15 | 176..1051 | |
| blaNDM-1 | 4496..5308 | |
| blaOXA-1 | 917..1747 | |
| Quinolone resistance | QnrB66 | 13226..13870 |
| aac(6′)Ib-cr | 1878..2477 | |
| oqxB | 77466..79915 | |
| oqxA | 79939..81114 | |
| MLS - Macrolide, Lincosamide and Streptogramin B resistance | msr(E) | 6514..7989 |
| mph(E) | 8045..8929 | |
| Phenicol resistance | catB3 | 338..779 |
| catA1 | 750..1409 | |
| Sulphonamide resistance | sul1 | 25..861 |
| Tetracycline resistance | tet(D) | 1979..3163 |
| Trimethoprim resistance | dfrA12 | 1833..2330 |
| dfrA14 | 5978..6460 | |
| Others | Elongation factor G | 2687…4789 |
| Fluoroquinolone resistant (gyrA) (Ser83 → Phe & Asp87 → Ala) | 46525…44111 | |
| Fosfomycin resistance protein (FosA) | 15585…16004 | |
| Plasmids | IncFIB(Mar) | 1579..2017 |
| IncHI1B | 2932..3501 | |
| IncFIB(pKPHS1) | 32186..32745 | |
| IncFIB(K) | 4153..4712 | |
| IncFII(K) | 8938..9085 | |
| Phages | Vibrio phage henriette 12B8 (NC_021073) | 111576-120734 |
| Sphingomonas phage PAU (NC_019521) | 57324-63593 | |
| Bacillus phage G (NC_023719) | 94476-106610 | |
| Salisaeta icosahedral phage 1 (NC_017983) | 73831-84962 |