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A: The structure of LLO, it consists of four distinct domains, which have been called D1 to D4 and each of them, playing a different role in LLO functionally. B: The modified structure (RD-1) in contact with D2 domain of LLO. C: The unbound RD-1 structure. D: The overall pharmacological properties of RD-1. E: The ligand map of RD-1. F: The structure of Hit#1. G: The structure of Hit#2. H: The structure of Hit#3. I: The structure of Hit#4. J: The structure of Hit#5
