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. Author manuscript; available in PMC: 2017 Jul 6.
Published in final edited form as: Nature. 2017 Jan 18;541(7637):339–346. doi: 10.1038/nature21351

Figure 1. Structures of base-modified nucleosides known to be present at internal positions in mRNA.

Figure 1

Six modified bases have been discovered so far: m6A, m1A and inosine (top row) and m5C, hm5C and pseudouridine (bottom row). Chemical modifications are shown in red. Relevant purine and pyrimidine ring numbering is shown in blue.