Figure 5.

In Vivo Biodistribution of I₆P₇-Stp-His/DNA NPs

(A) In vivo fluorescent images of glioma-bearing mice at different time points after intravenous (i.v.) administration of I₆P₇-Stp-His/DNA (left) and I₆P₇scr-Stp-His/DNA (right). (B) Ex vivo fluorescent images of the organs harvested at 3 hr after i.v. administration of I₆P₇-Stp-His/DNA (top) and I₆P₇scr-Stp-His/DNA NPs (bottom). (C) Fluorescence quantitative analysis of ex vivo organs of U87 tumor-bearing mice at different time intervals after intravenous injection. DNA was pre-labeled by YOYO-3.