Figure 1.

8-pCPT-cGMP attenuates injury of fatty partial liver grafts after transplantation. Rats were fed a low-fat, low-fructose control diet or a high-fat, high-fructose diet for 2 weeks. A: Livers were collected 38 h after sham operation or transplantation. Shown are representative images of H+E-stained liver sections. Arrows identify necrotic areas. Bar is 100 µm. B: Blood was collected at 18 h after sham operation or transplantation for measurement of alanine aminotransferase (ALT) in sera. Sham, sham operation; Lean, lean liver; Fatty, fatty liver; LPG, lean partial graft; FPG, fatty partial graft; 8CG, 8-pCPT-cGMP. a, P<0.05 vs sham-operated lean livers; b, P<0.05 vs sham-operated fatty livers; c, P<0.05 vs LPG, and d, P<0.05 vs FPG (n = 4/group).