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. 2017 Jul 5;10:323. doi: 10.1186/s13071-017-2246-x

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Dose-response curves for compounds SNS-032 (MMV690767) and AG-1295 (MMV079840) on larval stages of Haemonchus contortus in vitro with reference to the positive-control compound monepantel. Inhibition of motility of (a) third-stage (xL3) and (b) fourth-stage (L4) larvae at 72 h and of development of fourth-stage larvae (L4s) at 7 days (c) of exposure to each of the compound. Assessment of the toxicity of compounds SNS-032 (MMV690767) and AG-1295 (MMV079840) on breast epithelial (MCF10A) cells after 48 h of exposure to each compound in vitro (d). Each data point represents the mean of two to five experiments repeated in triplicate on different days (± standard error of the mean, SEM)