Table 2. Eye-specific knockdown of several Drosophila chaperones result in eye morphological defects.

Sr. No.	VDRC Line	Gene	Representative Eye Phenotype	% Flies Showing Eye Morphology Defects
Heat shock protein 70 chaperones
1	GD50382	CG31449	Rough/large eye	100
2	KK106510	CG8937	Eyeless	100
3	GD27680	CG6603	Severely deformed eye	40
Heat shock protein 60 chaperonins
4	GD45789	CG8258	Severely deformed eye	80
5	GD36071	CG8977	Rough eye	100
Prefoldin
6	GD51825	CG15266	Ectopic bristles in eyes	50
7	KK106186	CG15266	Deformed eye	100
Heat shock protein40/DnaJ cochaperones
8	KK101532	CG5001	Eyeless	100
9	KK109817	CG8448	Deformed eye	90
10	GD40051	CG17187	Severely deformed eye	100
11	KK107706	CG8014	Liquid facet-like phenotype	100
12	KK104880	CG8863	Deformed eye	100
13	KK107020	CG7556	Severely deformed eye	90
14	KK101490	CG7394	Small eye, reduced number of ommatidia	100
15	KK110331	CG8583	Rough and deformed eye	100

ey-Gal4-driven knockdown identified essential chaperones required for regulating eye morphology and/or rhabdomere development. Knockdown of some of these candidate genes using ey-Gal4 also leads to partial pupal lethality. Sr., serial number; No., number; VDRC, Vienna Drosophila Resource Center.