Table 4. Deleterious and tolerated SNPs grouped according to Europe (EU)/Asia (AS) continent and domestic (DM)/wild (WB) status.

Continent	Population	SNP Typea	Nonsignificant Genes of Nonsignificant Pathways	Significant Genes of Nonsignificant Pathways	Nonsignificant Genes of Significant Pathways	Significant Genes of Significant Pathways	P-Valueb
Asia	ASDM	Tolerated	8534	1,195	2,625	1,176	0.756
		Deleterious	6,825	954	2,144	927
		λASDM	0.800	0.798	0.817	0.788
	ASWB	Tolerated	6,245	843	2,029	636	0.033
		Deleterious	4,432	587	1,320	391
		λASWB	0.710	0.696	0.651	0.615
	ASDM/ASWB	λASDM/λASWB	1.127	1.147	1.255	1.282
Europe	EUDM	Tolerated	5,191	716	1,675	620	0.023
		Deleterious	3,429	483	1,200	349
		λEUDM	0.661	0.675	0.716	0.563
	EUWB	Tolerated	2,654	416	893	346	0.001
		Deleterious	1,153	198	382	103
		λEUWB	0.434	0.476	0.428	0.298
	EUDM/EUWB	λEUDM/λEUWB	1.523	1.418	1.675	1.891
Total	Total	Tolerated	22,624	3,170	7,222	2,778	0.003
		Deleterious	15,839	2,222	5,046	1,770
		λTotal	0.700	0.701	0.699	0.637

SNP, single nucleotide polymorphism; ASDM, Asian domestic; ASWB, Asian wild boar; EUDM, European domestic; EUWB, European wild boar.

^aλ corresponds to the ratio of deleterious vs. tolerated SNPs.

^bP-value obtained from χ² test of the 2 × 2 table containing nonoverlapping SNP sets (nonsignificant genes from nonsignificant pathways vs. significant genes from significant pathways).