Figure 1.
Schematic of the assayed components of the IIS/TOR pathway and their proposed interactions in D. melanogaster. Arrows indicate activation and bar-ended lines indicate inhibition. Dashed lines indicate indirect or uncertain interactions. Mipp2, Tor, REPTOR, and rictor all form components of TOR-C1 and/or TOR-C2 and are not shown separately in the schematic. Adapted from Teleman (2010) and Nässel et al. 2015.