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. 2017 Apr 3;206(2):785–800. doi: 10.1534/genetics.117.201285

Table 2. Rates of interhomolog and intra/sister chromatid in cells grown in medium without added copper, and in medium with 1.4 mM copper.

Strain Relevant genotype Condition CEN8-hphMX4 interhomolog hphMX4-URA3 interhomolog URA3-kanMX4/CAN1 interhomolog hphMX4-kanMX4/CAN1 interhomolog Intra/sister chromatid
YZ103 Wild-type No added copper 1.1 × 10−5 (0.9–1.7) [1] 5.1 × 10−6 (4.4–7.0) [1] 6.0 × 10−6 (4.4–8.1) [1] 1.1 × 10−5 [1] 1.0 × 10−4 (0.7–1.2) [1]
YZ103 Wild-type 1.4 mM copper sulfate 1.3 × 10−5 (1.1–1.6) [1.2] 8.6 × 10−5 (7.4–11) [17] 8.8 × 10−5 (7.5–11) [15] 1.7 × 10−4 [15] 2.3 × 10−3 (2.0–2.7) [23]
YZ117 cup2/cup2 No added copper 8.8 × 10−6 (6.2–13) [0.8] 3.6 × 10−6 (2.3–4.8) [0.71] 4.2 × 10−6 (3.1–5.7) [0.7] 7.8 × 10−6 [0.71] 1.1 × 10−4 (0.7–1.4) [1.1]
YZ118 cup2/cup2 + p425-GPD-CUP1 No added copper 6.8 × 10−6 (4.6–10) [0.62] 4.3 × 10−6 (2.7–4.9) [0.84] 4.1 × 10−6 (3.1–5.2) [0.68] 8.4 × 10−6 [0.76] 6.7 × 10−5 (5.0–7.7) [0.67]
YZ118 cup2/cup2 + p425-GPD-CUP1 1.4 mM copper sulfate 1.3 × 10−5 (0.9–2.5) [1.2] 1.2 × 10−5 (1.1–1.6) [2.4] 9.9 × 10−6 (6.9–11) [1.7] 2.2 × 10−5 [2] 8.4 × 10−5 (7.3–10) [0.84]

Numbers in parentheses after the rate estimates are the 95% C.I. Numbers in square brackets in bold are the rates divided by the rate observed in YZ103 grown in medium without added copper. The number of cells per culture was determined using synthetic dextrose-complete medium containing 0.2 mM copper.