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Homologous OleC enzymes encoded in β-lactone biosynthesis gene clusters. Percent iden-tity is based on amino acid sequences. The E values for OleC to LstC and Orf1 are 2e-72 and 1e-143, respectively. Lipstatin is the precursor to the anti-obesity drug Orlistat. Ebelactone A is a commercially available general esterase inhibitor.
