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. Author manuscript; available in PMC: 2017 Jul 6.
Published in final edited form as: Math Biosci. 2010 Mar 25;226(1):1–15. doi: 10.1016/j.mbs.2010.03.005

Fig. 7.

Fig. 7

Mechanisms of interval–force relations shown by changing pacing frequency from 1.0 Hz to 2.0 Hz (from 9 to 24 s) and back to 1.0 Hz. (A) Normalized force, (B) bulk myoplasmic calcium concentration, (C) fraction of open ryanodine receptor channels, (D) fraction of ryanodine receptor channels in adapted state, and (E) junctional SR calcium concentration.