Fig. 3. Time-kill kinetics of (Glc)Ent–Amp against E. coli CFT073 and UTI89. (a and b) Time-kill kinetics of (Glc)Ent–Amp 5/7/9 against (a) uropathogenic E. coli CFT073 (≈108 CFU mL–1) treated with 50 μM Amp or 5 μM (Glc)Ent–Amp 5/7/9 and (b) uropathogenic E. coli UIT89 (≈108 CFU mL–1) treated with 50 μM Amp or 50 μM (Glc)Ent–Amp 5/7/9. All assays were performed in 50% MHB medium supplemented with 200 μM DP (T = 37 °C) (mean ± standard deviation, n ≥ 3). The data for (Glc)Ent–Amx 6/8/10 and for the assays performed in the absence of DP are presented in Fig. S13–S14.† .
