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. 2016 Jun 12;2(1):vew019. doi: 10.1093/ve/vew019

Figure 3.

Figure 3.

DNA polymerase domain of Tlr1-like helicases. (A) Domain organizations of Tlr1-like helicases from various elements and their comparison to pDNAPs of tectivirus PRD1 and Polinton 1-TC. Conserved motifs of the exonuclease and polymerization domains are indicated with Roman and Arabic numbers, respectively. Open circles indicate that the particular motif is missing. TPR1, TPR2 and TP (terminal protein) domains are also shown. (B) Multiple sequence alignment of the conserved motifs from pDNAP domains of Tlr1-like helicases and pDNAPs encoded by various viruses and plasmids. Sequences are identified with their GI identifiers. The conserved motifs are indicated above the alignment. The alignment is colored according to sequence conservation using the standard Clustal color scheme.