Table II. Islet antigen peptides used for stimulation.
Peptide | Protein | Pool | Start | End | Length | Sequence | Reference |
---|---|---|---|---|---|---|---|
p1 | GAD651 | GAD1 | 1 | 20 | 20 | MASPGSGFWSFGSEDGSGDS | (44) |
p10 | GAD65 | GAD1 | 73 | 92 | 20 | CACDQKPCSCSKVDVNYAFL | (44) |
p14 | GAD65 | GAD1 | 105 | 124 | 20 | RPTLAFLQDVMNILLQYVVK | (44) |
p15 | GAD65 | GAD1 | 113 | 132 | 20 | DVMNILLQYVVKSFDRSTKV | (44) |
p34 | GAD65 | GAD1 | 265 | 284 | 20 | KGMAALPRLIAFTSEHSHFS | (44) |
p35 | GAD65 | GAD2 | 273 | 292 | 20 | LIAFTSEHSHFSLKKGAAAL | (44) |
p36 | GAD65 | GAD2 | 281 | 300 | 20 | SHFSLKKGAAALGIGTDSVI | (44) |
p37 | GAD65 | GAD2 | 289 | 308 | 20 | AAALGIGTDSVILIKCDERG | unpublished |
p38 | GAD65 | GAD2 | 297 | 316 | 20 | DSVILIKCDERGKMIPSDLE | (44) |
p39 | GAD65 | GAD2 | 305 | 324 | 20 | DERGKMIPSDLERRILEAKQ | (44) |
p41 | GAD65 | GAD3 | 321 | 340 | 20 | EAKQKGFVPFLVSATAGTTV | (44) |
p45 | GAD65 | GAD3 | 353 | 372 | 20 | ICKKYKIWMHVDAAWGGGLL | (44) |
p47 | GAD65 | GAD3 | 369 | 388 | 20 | GGLLMSRKHKWKLSGVERAN | (44) |
p48 | GAD65 | GAD3 | 377 | 396 | 20 | HKWKLSGVERANSVTWNPHK | (44) |
p55 | GAD65 | GAD4 | 433 | 452 | 20 | YDLSYDTGDKALQCGRHVDV | (44) |
p60 | GAD65 | GAD4 | 473 | 492 | 20 | KCLELAEYLYNIIKNREGYE | (44) |
p69 | GAD65 | GAD4 | 545 | 564 | 20 | VSYQPLGDKVNFFRMVISNP | (44) |
p70 | GAD65 | GAD4 | 553 | 572 | 20 | KVNFFRMVISNPAATHQDID | (44) |
p3 | IGRP2 | IGRP | 17 | 36 | 20 | KDYRAYYTFLNFMSNVGDPR | (45) |
p31 | IGRP | IGRP | 241 | 260 | 20 | KWCANPDWIHIDTTPFAGLV | (45) |
p39 | IGRP | IGRP | 305 | 324 | 20 | QLYHFLQIPTHEEHLFYVLS | unpublished |
np1 | ZNT83 | ZNT8 | 1 | 20 | 20 | MEFLERTYLVNDKAAKMYAF | unpublished |
np2 | ZNT8 | ZNT8 | 9 | 28 | 20 | LVNDKAAKMYAFTLESVELQ | unpublished |
np3 | ZNT8 | ZNT8 | 17 | 36 | 20 | MYAFTLESVELQQKPVNKDQ | unpublished |
p20 | ZNT8 | ZNT8 | 202 | 221 | 20 | GHNHKEVQANASVRAAFVHA | unpublished |
p28 | ZNT8 | ZNT8 | 266 | 285 | 20 | ILKDFSILLMEGVPKSLNYS | unpublished |
p36 | ZNT8 | ZNT8 | 330 | 349 | 20 | VRREIAKALSKSFTMHSLTI | unpublished |
p28 | PPI4 | GAD4 | 76 | 90 | 15 | SLQPLALEGSLQKRG | (43) |
GAD65, GAD, glutamate decarboxylase 2, NP_000809.1
IGRP, G6PC2, glucose-6-phosphatase 2 isoform 1, NP_066999.1
ZNT8, SLC30A8, zinc transporter 8 isoform a, NP_776250.2
PPI, INS, insulin preproprotein, NP_000198.1