Figure 1. Representative results: RNA exosomes purified from HEK-293 cells expressing EXOSC10-3xFLAG.

A. Schematic diagram of a stained SDS-polyacrylamide gel demonstrating protein bands consistent with the separation of EXOSC10-3xFLAG purified RNA exosomes obtained after sedimentation within a 10-40% v/v glycerol gradient. B. The original gel, reproduced from Domanski et al., 2016 . Separated proteins were visualized by silver staining. The arrow indicates the peak fraction.