Fig. 2.

DROSHA mRNA expression in HPV negative C33A cervical cancer cells with transient expression of HPV16 E6/E7. C33A cells were transiently transfected with empty vector (C), HPV16 E6 alone (E6), HPV16 E7 alone (E7) or both HPV16 E6/E7 (E6/E7). DROSHA mRNA levels were analyzed by RT-qPCR. Expression of 18S ribosomal RNA (18S) was utilized as a control and values were normalized to control vector transduced C33A cells. Results represent averages of three independent experiments and error bars show standard deviation. * and ** indicate statistical significance at a P<0.05 and P<0.01, respectively. “NS”: Not Statistically Significant.