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. 2017 May 17;45(11):6981–6992. doi: 10.1093/nar/gkx430

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© The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Distributions of mRNA (yEGFP) counts per cell. (A) Overlaying the distributions for P_TEF1(L0) and P_TEF1(M3) reveals no significant effect of inserting the M3 stem–loop structure into the 5΄UTR. Panels B and C show the corresponding data for P_PAB1(L0) and P_DCD1(L0), respectively. (D) Overview of the data shown in A–C. The key statistical data are summarized in Table 1. The data obtained with the P_TEF1 and P_PAB1 promoters fit to negative binomial distributions (A, B). In the case of P_DCD1(C), it is difficult to distinguish between negative binomial and Poissonian fits.