Table 1. N2-modified DNA sequences.
Name | Sequence (5΄- 3΄) | Number of modifications | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Total | MET | BEN | HEX | BIO | ||||||||||
Native | TT | GGG | TTA | GGG | TTA | GGG | TTA | GGG | A | |||||
Single-Position | ||||||||||||||
Met-3 | TT | MGG | TTA | GGG | TTA | GGG | TTA | GGG | A | 1 | 1 | |||
Met-4 | TT | GMG | TTA | GGG | TTA | GGG | TTA | GGG | A | 1 | 1 | |||
Met-5 | TT | GGM | TTA | GGG | TTA | GGG | TTA | GGG | A | 1 | 1 | |||
Met-9 | TT | GGG | TTA | MGG | TTA | GGG | TTA | GGG | A | 1 | 1 | |||
Met-10 | TT | GGG | TTA | GMG | TTA | GGG | TTA | GGG | A | 1 | 1 | |||
Met-11 | TT | GGG | TTA | GGM | TTA | GGG | TTA | GGG | A | 1 | 1 | |||
Met-15 | TT | GGG | TTA | GGG | TTA | MGG | TTA | GGG | A | 1 | 1 | |||
Met-16 | TT | GGG | TTA | GGG | TTA | GMG | TTA | GGG | A | 1 | 1 | |||
Met-17 | TT | GGG | TTA | GGG | TTA | GGM | TTA | GGG | A | 1 | 1 | |||
Met-21 | TT | GGG | TTA | GGG | TTA | GGG | TTA | MGG | A | 1 | 1 | |||
Met-22 | TT | GGG | TTA | GGG | TTA | GGG | TTA | GMG | A | 1 | 1 | |||
Met-23 | TT | GGG | TTA | GGG | TTA | GGG | TTA | GGM | A | 1 | 1 | |||
Ben-3 | TT | BGG | TTA | GGG | TTA | GGG | TTA | GGG | A | 1 | 1 | |||
Ben-4 | TT | GBG | TTA | GGG | TTA | GGG | TTA | GGG | A | 1 | 1 | |||
Ben-5 | TT | GGB | TTA | GGG | TTA | GGG | TTA | GGG | A | 1 | 1 | |||
Ben-9 | TT | GGG | TTA | BGG | TTA | GGG | TTA | GGG | A | 1 | 1 | |||
Ben-10 | TT | GGG | TTA | GBG | TTA | GGG | TTA | GGG | A | 1 | 1 | |||
Ben-11 | TT | GGG | TTA | GGB | TTA | GGG | TTA | GGG | A | 1 | 1 | |||
Ben-15 | TT | GGG | TTA | GGG | TTA | BGG | TTA | GGG | A | 1 | 1 | |||
Ben-16 | TT | GGG | TTA | GGG | TTA | GBG | TTA | GGG | A | 1 | 1 | |||
Ben-17 | TT | GGG | TTA | GGG | TTA | GGB | TTA | GGG | A | 1 | 1 | |||
Ben-21 | TT | GGG | TTA | GGG | TTA | GGG | TTA | BGG | A | 1 | 1 | |||
Ben-22 | TT | GGG | TTA | GGG | TTA | GGG | TTA | GBG | A | 1 | 1 | |||
Ben-23 | TT | GGG | TTA | GGG | TTA | GGG | TTA | GGB | A | 1 | 1 | |||
Hex-3 | TT | HGG | TTA | GGG | TTA | GGG | TTA | GGG | A | 1 | 1 | |||
Hex-4 | TT | GHG | TTA | GGG | TTA | GGG | TTA | GGG | A | 1 | 1 | |||
Hex-5 | TT | GGH | TTA | GGG | TTA | GGG | TTA | GGG | A | 1 | 1 | |||
Hex-9 | TT | GGG | TTA | HGG | TTA | GGG | TTA | GGG | A | 1 | 1 | |||
Hex-10 | TT | GGG | TTA | GHG | TTA | GGG | TTA | GGG | A | 1 | 1 | |||
Hex-11 | TT | GGG | TTA | GGH | TTA | GGG | TTA | GGG | A | 1 | 1 | |||
Hex-15 | TT | GGG | TTA | GGG | TTA | HGG | TTA | GGG | A | 1 | 1 | |||
Hex-16 | TT | GGG | TTA | GGG | TTA | GHG | TTA | GGG | A | 1 | 1 | |||
Hex-17 | TT | GGG | TTA | GGG | TTA | GGH | TTA | GGG | A | 1 | 1 | |||
Hex-21 | TT | GGG | TTA | GGG | TTA | GGG | TTA | HGG | A | 1 | 1 | |||
Hex-22 | TT | GGG | TTA | GGG | TTA | GGG | TTA | GHG | A | 1 | 1 | |||
Hex-23 | TT | GGG | TTA | GGG | TTA | GGG | TTA | GGH | A | 1 | 1 | |||
Multiple | ||||||||||||||
N2-One-Groove | TT | GGG | TTA | GMM | TTA | GGG | TTA | GGG | A | 2 | 2 | |||
N2-Two-Groove | TT | HGG | TTA | HGG | TTA | GGG | TTA | GGG | A | 2 | 2 | |||
N2-All-Groove | TT | HGG | TTA | HGM | TTA | MGG | TTA | GGG | A | 4 | 2 | 2 | ||
N2-Ball-with-Hair | TT | HHG | TTA | HGH | TTA | HGH | TTA | GHH | A | 8 | 8 | |||
Functional | ||||||||||||||
Bio-22 | TT | GGG | TTA | GGG | TTA | GGG | TTA | GOG | A | 1 | 1 | |||
Bio-11-22 | TT | GGG | TTA | GGO | TTA | GGG | TTA | GOG | A | 2 | 2 |