Figure 2.

Differences in codon usage bias between lowly and highly translated genes. (A) Euclidean distance between RSCU_RS of lowly and highly translated genes was computed for ten species. This distance clearly partitions the species in two groups: the mean euclidean distance is 1.51 for group 1 (left, in orange), and is 6.64 for group 2 (right, in grey). Group 2 comprises C. albicans, S. cerevisiae, S. pombe and C. elegans, while group 1 comprises all vertebrates, D. melanogaster, P. falciparum and H. capsulatum. (B) For each species, comparison of the RSCU_RS of all codons between lowly and highly translated genes (ltg vs htg). Codons from group 1 species (containing the vertebrates) are shown as orange circles, while codons from group 2 species (that of the budding yeast) as gray circles. A point near the diagonal indicates a similar behavior in ltg and htg. The further apart the point from the diagonal, the higher the bias of that codon. Refer to the online version for colors.