Fig. 6.

—Summary of Dbl-like RhoGEF gain and loss events across eukaryote supergroups. A global view of the phylogeny of supergroups and taxa examined is presented, with the timeline of eukaryote emergence. Gain (in blue) and loss (in red) events that have built the repertoires of extant species are indicated. ¹: In Holometabola and Paraneoptera, and ²: In Chlamydomonales. The number of subfamilies, as defined in figure 1, is indicated for Metazoa. Green dots indicate nodes important for inferring the expansion of the Dbl family in Metazoa.