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. 2017 Jun 27;5(1):cox036. doi: 10.1093/conphys/cox036

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© The Author 2017. Published by Oxford University Press and the Society for Experimental Biology.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 10: — Gene network constructed based a 27-gene VDD panel identified to mammalian genes based on their gene symbols, showing key regulators (IFNG highlighted in green) and nearest neighbors (no highlight) overlaid onto the cell to show localization of protein activity. Analysis performed in Pathway Studio (Elsevier, Amsterdam). Fourteen VDD genes mapping to mammalian genes (IFH1, HERC6, RSAD2, DDX58, CD9, MX1, IFIT5, STAT1, XAF1, MX1, RNF213, TRIM21, USP18) are found within this gene network (highlighted in blue).