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LC–MS/MS and LC–MS/MS/MS analysis results of the nucleoside mixture arising from the enzymatic digestion of cross-linked duplex E. (A) The selected-ion chromatogram for the m/z 370→254 transition. (B) The selected-ion chromatogram for the m/z 370→254→136 transition. Shown in the insets are the MS/MS (A) and MS/MS/MS (B) averaged from the 23.8-min fraction. (C) Possible structures for the ions observed at m/z 370, 254 and 136.
