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The cell migration and invasion assays revealed that the metastasis ability was restricted in combined therapy group in both LN229 and U251 cells. The γ-irradiation (18Gy) group showed more tendency to metastasize than NC group and CCM (20 μM) group. Adding with Curcumin (20 μM), combined therapy showed the least metastasis ability. * meant P value was less than 0.05 compared with NC group. ** meant P value was less than 0.01 compared with NC group.
