Table 1. Analysis of lifespan using the Log-rank test.
Experimental Group | Number of Flies Tested (n) | Median Lifespan (d) | % Change | χ2 | Log-Rank |
---|---|---|---|---|---|
elav > shPsn2 (Figure 3E) | |||||
elav-Gal4/+ | 150 | 86 | |||
+/+;; UAS-shPsn2/+ | 143 | 90 | 4.65 | 2.6 | P = 0.1079 |
elav-Gal4/+;; UAS-shPsn2/+(EW) | 114 | 22 | −75.56 | 345.7 | P < 0.0001 |
elav-Gal4/+;; UAS-shPsn2/+(WW) | 65 | 5 | −77.27 | 292.1 | P < 0.0001 |
elav > shPsn3 male (Figure 4D) | |||||
elav-Gal4/y | 118 | 62 | |||
+/y; UAS-shPsn3/+ | 119 | 56 | −9.68 | 6.9 | P < 0.01 |
elav-Gal4/y; UAS-shPsn3/+ | 99 | 23 | −58.93 | 214.1 | P < 0.0001 |
elav > shPsn3 female (Figure 4E) | |||||
elav-Gal4/+ | 147 | 87 | |||
+/+; UAS-shPsn3/+ | 149 | 83 | −4.60 | 36.5 | P < 0.0001 |
elav-Gal4/+; UAS-shPsn3/+ | 156 | 62 | −19.48 | 284.4 | P < 0.0001 |
AN-Psn cKD (Figure 7D) | |||||
elav-Gal4/y;; tub-Gal80ts/+ (control) | 198 | 53 | |||
elav-Gal4/y;; tub-Gal80ts/UAS-shPsn2 | 222 | 46 | −13.21 | 146.4 | P < 0.0001 |
AN-Nct cKD (Figure 7E) | |||||
elav-Gal4/y;; tub-Gal80ts/+ (control) | 233 | 51 | |||
elav-Gal4/y;; tub-Gal80ts/UAS-shNct2 | 197 | 46 | −9.80 | 76.6 | P < 0.0001 |
AN-Psn/Nct cKD (Figure 7F) | |||||
elav-Gal4/y;; tub-Gal80ts/+ (control) | 169 | 51 | |||
elav-Gal4/y;; tub-Gal80ts, UAS-shPsn2/UAS-shNct2 | 123 | 32 | −37.26 | 388.0 | P < 0.0001 |
% change shows differences in median lifespan between control and experimental groups. P values were determined in each comparison between the control and the experimental group by the Mantel-Cox test.